Ga-68-DOTATOC -PET in the Management of Pituitary Tumours
Launched by GÖTEBORG UNIVERSITY · Apr 14, 2015
Trial Information
Current as of May 20, 2025
Terminated
Keywords
ClinConnect Summary
Background The most common cause to pituitary insufficiency is the pituitary adenoma (PA). PA may be divided into hormone producing PAs and non-functioning PAs (NFPA). Normal pituitary tissue, as well as tissues from PAs, expresses somatostatin receptors (sst). Five subtypes of sst receptors has been characterized.
Magnetic resonance tomography (MRI) presents anatomy, while in vivo diagnostics with somatostatin receptor scintigraphy (SRS) or position emission tomography (PET) reflect the functional properties of the tissue. The SRS have earlier been evaluated for diagnostics of pituitary d...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Naïve, unoperated pituitary tumour with GH or ACTH or TSH production or NFPA without treatment with somatostatin analogues or dopamine agonists.
- Exclusion Criteria:
- • Patient who may not attend to the protocol according to the investigators opinion.
- • Pregnancy or lactating
- • Isolated prolactin producing tumours
- • Overproduction of gonadotrophins
- • Carcinoids ie ectopic CRF production
- • Known or suspected allergy to the trial product or related products.
About Göteborg University
Göteborg University, a leading academic institution in Sweden, is committed to advancing healthcare through innovative research and clinical trials. With a strong focus on interdisciplinary collaboration, the university leverages its extensive expertise in various fields, including medicine, pharmacology, and social sciences, to address pressing health challenges. By sponsoring clinical trials, Göteborg University aims to contribute to the development of new therapies and improve patient outcomes, while adhering to the highest ethical standards and regulatory requirements. Their dedication to rigorous scientific inquiry and community engagement positions them as a pivotal player in the global health research landscape.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Göteborg, , Sweden
Patients applied
Trial Officials
Helena Filipsson Nyström, Ass Prof
Principal Investigator
Center of Endocrinology and Metabolism, Dep of Endorinology, Sahlgrenska University Hospital, Göteborg, Sweden
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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