Tip-flexible Semi-rigid Ureterorenoscope Versus Flexible Ureteroscopy in Renal Calculi

Launched by LING LI, MD · Apr 22, 2015

Keywords

ClinConnect Summary

Retrograde intrarenal surgery using flexible ureteroscope has become the first-line treatment for renal calculi \< 3.0 cm and is recommended by the European Association of Urology due to its minimally-invasive nature and satisfactory result.

However, some limitations still remain. Poor maneuverability, extra costs for the ureteral access sheath, and high device vulnerability still preclude flexible ureteroscopy from wider distribution.

Recently, the investigators present a novel ureterorenoscope, which is composed of a retractable rigid sheath and a semi-rigid ureteroscope with a flexible...

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Eligibility criteria

• Inclusion Criteria:
• • Subject has provided informed consent and indicated a willingness to comply with study treatments
• • Subject has a diagnosis of renal stones according to computer tomography (CT) and intravenous pyelogram (IVP) results
• • Subject is a surgical candidate for the ureteroscopic approach
• • Subject is 18-80 yrs of age
• • Subject has a single stone \< 3 cm in size (IVP), or multiple stones \< 3 cm in cumulative size (IVP)
• • Subject has a serum creatinine level within the normal range for the study center
• Exclusion Criteria:
• • Subject needs bilateral procedures within one-stage ureteroscopy
• • Subject has an active urinary tract infection (e.g., cystitis, prostatitis, urethritis, etc.)
• • Subject has been diagnosed with a urethral stricture or bladder neck contracture
• • Subject has been diagnosed with a urinary tract infection related to stone obstruction within two weeks
• • Subject has severe hematuria that might blur the vision of the endoscopy
• • Subject has a disorder of the coagulation cascade system that would put the subject at risk for intraoperative or postoperative bleeding
• • Subject is unable to discontinue anticoagulant and antiplatelet therapy preoperatively (3-5 d)
• • Subject has other diseases and could not tolerate the endoscopic surgery
• • Subject has any kind of anatomic abnormality of the urinary system that might have an influence on the surgery
• • Subject has ipsilateral pre-stenting or previous ureteroscopy within six months
• • Subject has been diagnosed with hydronephrosis larger than 3 cm according to the B-scan ultrasonography examination