Covered Stents Versus Bare-Metal Stents
Launched by ERASMUS MEDICAL CENTER · Apr 28, 2015
Trial Information
Current as of May 12, 2025
Unknown status
Keywords
ClinConnect Summary
Symptomatic chronic atherosclerotic gastrointestinal ischemia (CGI) is an uncommon, potentially underdiagnosed condition caused by fixed stenosis or occlusion of in most conditions at least one of the three gastrointestinal arteries. Atherosclerosis is a predisposing factor for CGI. Clinical symptoms can vary widely. Typical symptoms are postprandial abdominal pain, unintended weight loss and food avoidance. But atypical abdominal pain such as exercise related pain, diarrhoea and nausea can also indicate CGI. The use of endovascular techniques for revascularization of chronic stenosis and o...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients with consensus diagnostic of CGI based on a clinical meeting with a gastroenterologist, a vascular surgeon and an interventional radiologist.
- • Diagnostic consensus of CGI is based on.
- • Presence of postprandial pain
- • Unexplained weight loss (\>5% of normal body weight).
- • Significant stenosis of \>50% of at least one of the gastrointestinal arteries on a recent CTA (Computer Tomographic Angiography) not older than one year, with maximum slice thickness 1 mm and enhancement in aorta of 300HU (Hounsfields Units)
- • Mucosal ischemia detected by VLS (Visible Light Spectroscopy) or tonometry
- • Patients over the age of 18 years.
- • Patients who gave informed consent.
- • Patients have sustained atherosclerosis.
- Exclusion Criteria:
- • Patients who don't give informed consent.
- • Age \< 18 years
- • No stenosis detected during arteriography.
- • Renal insufficiency (GFR below 30 ml/min or GFR below 60 ml/min when comorbidities relevant to kidney function present).
- • Previous stent placement in the to be treated gastrointestinal artery.
- • Pregnancy
- • Celiac artery compression syndrome.
- • Vasculitis
About Erasmus Medical Center
Erasmus Medical Center, located in Rotterdam, Netherlands, is a leading academic medical center renowned for its commitment to advancing healthcare through innovative research and clinical trials. As a prominent institution within the Erasmus University Rotterdam, the center integrates cutting-edge scientific inquiry with comprehensive patient care, focusing on a wide range of medical specialties. With a strong emphasis on multidisciplinary collaboration, Erasmus Medical Center aims to translate research findings into tangible clinical applications, enhancing treatment options and improving patient outcomes. The institution is dedicated to conducting ethical and rigorous clinical trials that contribute to the global body of medical knowledge and foster advancements in personalized medicine.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Rotterdam, Zuid Holland, Netherlands
Patients applied
Trial Officials
Adriaan Moelker, dr
Principal Investigator
Erasmus Medical Center
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Similar Trials