Ridge Augmentation: Particulate v/s Block Graft
Launched by UNIVERSITY OF LOUISVILLE · Jun 29, 2015
Trial Information
Current as of April 24, 2025
Completed
Keywords
ClinConnect Summary
30 patients will be treated using the principles of guided bone regeneration and ridge augmentation. 15 test patients will receive a corticocancellous particulate allograft mixed with autogenous bone chips. The positive control group of 15 patients will receive a cancellous block allograft. Both the groups will receive a hd-PTFE (Cytoplast) barrier membrane. An allograft can be defined as bone that can be obtained from a different individual of the same species (human donor bone) whereas a autograft can be defined as bone that can be obtained from the same individual. Following flap reflect...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • At least a one tooth area with a ridge defect, treatment planned to receive a dental implant. The site must be bordered by at least one tooth.
- • Healthy person that is at least 18 years old.
- • Patient understands and signs an informed consent approved by the University of Louisville Human Studies Committee.
- Exclusion Criteria:
- • Patients with debilitating systemic diseases, diseases that significantly affect the periodontium, or psychological problems that would interfere with treatment.
- • Previous head and neck radiation or chemotherapy within the previous 12 months.
- • Patients with known allergy to any of the materials that will be used in the study.
- • Smokers.
- • Patients on oral bisphosphonates \> 3 years or any IV bisphosphonates.
- • Patients who are pregnant.
Trial Officials
Henry Greenwell, DMD, MSD
Principal Investigator
Director of Graduate Periodontics, School of Dentistry, University of Louisville.
About University Of Louisville
The University of Louisville is a distinguished academic institution known for its commitment to advancing medical research and clinical innovation. As a clinical trial sponsor, the university leverages its extensive resources and expertise to conduct pioneering studies that aim to improve patient outcomes and enhance healthcare practices. With a focus on interdisciplinary collaboration and community engagement, the University of Louisville fosters an environment conducive to groundbreaking research across various medical fields, ensuring adherence to the highest ethical standards and regulatory compliance. Through its clinical trials, the university seeks to translate scientific discoveries into tangible benefits for patients and the broader community.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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