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Search / Trial NCT02496923

High Flow Nasal Oxygen Therapy (Optiflow™) in High-risk Cardiac Surgical Patients

Launched by PAPWORTH HOSPITAL NHS FOUNDATION TRUST · Jul 9, 2015

Trial Information

Current as of May 26, 2025

Completed

Keywords

Prophylactic Nhfo Risk Of Developing Postoperative Pulmonary Complications Reduces Hospital Length Of Stay

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients are eligible for inclusion if:
  • they are aged over 18 years
  • are undergoing elective cardiac surgery (coronary artery bypass grafting, valve surgery or both)
  • they have one or more patient-related risk factor for post-operative pulmonary complications (COPD, asthma, lower respiratory tract infection in last 4 weeks, body mass index≥35 kg/m2 current (last 6 weeks) heavy smokers (\> 10 packyears)).
  • they are capable of performing a 6MWT - The 6MWT is a clinical exercise test, and is popular in clinical practice because it aids clinical decision making, and because of the belief that it provides a better estimate of functional capacity than resting cardiorespiratory measurements (24). The 6MWT is the most popular clinical exercise test, which is used for postoperative evaluation after lung surgery and has also been validated in cardiac surgery
  • Exclusion Criteria:
  • Contraindication to high flow nasal oxygen such as nasal septal defect.
  • Not met extubation criteria by 10am the day after surgery (Day 1).
  • Need for CPAP pre-operatively.

About Papworth Hospital Nhs Foundation Trust

Papworth Hospital NHS Foundation Trust is a leading healthcare institution in the United Kingdom, renowned for its specialized services in cardiothoracic medicine and surgery. As a prominent clinical trial sponsor, the Trust is dedicated to advancing medical research and improving patient outcomes through innovative trials and studies. With a commitment to excellence in patient care, Papworth Hospital collaborates with various stakeholders, including academic institutions and pharmaceutical companies, to facilitate cutting-edge research that addresses critical health challenges. The Trust's experienced team of clinicians and researchers is focused on delivering high-quality evidence that contributes to the advancement of healthcare practices and therapies.

Locations

Cambridge, Cambridgeshire, United Kingdom

Patients applied

0 patients applied

Trial Officials

Vasileios Zochios, MD

Principal Investigator

Papworth Hospital NHS Foundation Trust, Papworth Everard, Cambridge, CB23 3RE, United Kingdom

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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