High Flow Nasal Oxygen Therapy (Optiflow™) in High-risk Cardiac Surgical Patients
Launched by PAPWORTH HOSPITAL NHS FOUNDATION TRUST · Jul 9, 2015
Trial Information
Current as of May 26, 2025
Completed
Keywords
ClinConnect Summary
No description provided
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- Patients are eligible for inclusion if:
- • they are aged over 18 years
- • are undergoing elective cardiac surgery (coronary artery bypass grafting, valve surgery or both)
- • they have one or more patient-related risk factor for post-operative pulmonary complications (COPD, asthma, lower respiratory tract infection in last 4 weeks, body mass index≥35 kg/m2 current (last 6 weeks) heavy smokers (\> 10 packyears)).
- • they are capable of performing a 6MWT - The 6MWT is a clinical exercise test, and is popular in clinical practice because it aids clinical decision making, and because of the belief that it provides a better estimate of functional capacity than resting cardiorespiratory measurements (24). The 6MWT is the most popular clinical exercise test, which is used for postoperative evaluation after lung surgery and has also been validated in cardiac surgery
- Exclusion Criteria:
- • Contraindication to high flow nasal oxygen such as nasal septal defect.
- • Not met extubation criteria by 10am the day after surgery (Day 1).
- • Need for CPAP pre-operatively.
About Papworth Hospital Nhs Foundation Trust
Papworth Hospital NHS Foundation Trust is a leading healthcare institution in the United Kingdom, renowned for its specialized services in cardiothoracic medicine and surgery. As a prominent clinical trial sponsor, the Trust is dedicated to advancing medical research and improving patient outcomes through innovative trials and studies. With a commitment to excellence in patient care, Papworth Hospital collaborates with various stakeholders, including academic institutions and pharmaceutical companies, to facilitate cutting-edge research that addresses critical health challenges. The Trust's experienced team of clinicians and researchers is focused on delivering high-quality evidence that contributes to the advancement of healthcare practices and therapies.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Cambridge, Cambridgeshire, United Kingdom
Patients applied
Trial Officials
Vasileios Zochios, MD
Principal Investigator
Papworth Hospital NHS Foundation Trust, Papworth Everard, Cambridge, CB23 3RE, United Kingdom
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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