Effect of Vitamin B12 Supplementation on Glycaemic Control in Uncontrolled Hyperhomocysteinemic Type 2 Diabetic Patients
Launched by SMT. KASHIBAI NAVALE MEDICAL COLLEGE AND GENERAL HOSPITAL · Sep 3, 2015
Trial Information
Current as of May 18, 2025
Completed
Keywords
ClinConnect Summary
After approval from Institutional Ethics Committee, patients not responding adequately to oral anti-diabetic agents were recruited from Medicine out patient department (OPD) with the help of treating physician. Patient were first screened for serum homocysteine/vitamin B12 level along with all baseline investigations. Those having serum homocysteine level more than 15 umol/L or vitamin B12 level less than 223pg/ml were enrolled in this study. Due to high cost for investigation serum homocysteine level was measured only in 6 patients and serum vitamin B12 level (cheaper test) was measured in...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. Age between 30 -70 years
- • 2. Sex: Male/ Non-lactating female
- • 3. Glycosylated hemoglobin (HbA1c) \> 8
- • 4. Serum Homocysteine \> 15 umol / L or vitamin B12 less than 223pg/ml
- Exclusion Criteria:
- • 1. Age \< 30 yrs.
- • 2. Pregnancy
- • 3. Lactating mother
- • 4. Patient with Insulin dependent diabetes mellitus
- • 5. Severe and Complicated diabetes mellitus
- • 6. Patient with hepatic or renal dysfunction
About Smt. Kashibai Navale Medical College And General Hospital
Smt. Kashibai Navale Medical College and General Hospital is a premier healthcare institution dedicated to advancing medical education, research, and patient care. Located in Pune, India, the college is affiliated with a leading university and offers comprehensive clinical training across various specialties. The hospital serves as a vital healthcare resource for the community, equipped with state-of-the-art facilities and a diverse team of experienced healthcare professionals. Committed to enhancing clinical knowledge and improving patient outcomes, Smt. Kashibai Navale Medical College and General Hospital actively engages in clinical trials that contribute to innovative medical research and the development of new treatment protocols.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Pune, Maharashtra, India
Patients applied
Trial Officials
YOGENDRA N KECHE, MD
Principal Investigator
SMT KASHIBAI NAVALE MEDICAL COLLEGE
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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