Pain Thresholds Under High-dose Topical Capsaicin
Launched by MEDICAL UNIVERSITY OF VIENNA · Oct 5, 2015
Trial Information
Current as of June 03, 2025
Completed
Keywords
ClinConnect Summary
Capsaicin is the main pungent ingredient in chili peppers. Topical capsaicin 8% is used for the treatment of peripheral neuropathic pain. Application of capsaicin 8% provokes distinct pain by activating the transient receptor potential vanilloid 1 (TRPV1) receptor. Cooling the skin results in a reliable prevention of the application pain. However, the necessary cooling temperature and if cooling itself produces application pain, is unknown.
Materials and Methods: 10 female and 10 male healthy volunteers will be enrolled in a randomised, double blind, placebo controlled, cross-over study. T...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • healthy volunteers 18 ore more years old
- Exclusion Criteria:
- • dermatologic or neurologic injuries on both thighs, (possible) pregnancy
About Medical University Of Vienna
The Medical University of Vienna is a leading research institution dedicated to advancing healthcare through innovative clinical research and education. Renowned for its commitment to excellence in medical science, the university fosters interdisciplinary collaboration among researchers, clinicians, and academic professionals. Its clinical trials encompass a wide range of medical disciplines, aiming to develop cutting-edge therapies and improve patient outcomes. With state-of-the-art facilities and a strong emphasis on ethical standards, the Medical University of Vienna is at the forefront of transforming scientific discoveries into practical applications that enhance global health.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Vienna, , Austria
Patients applied
Trial Officials
Erich Knolle, MD
Principal Investigator
Department of Anesthesia, Critical Care and Pain Medicine
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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