Pilot Study In Vivo Confocal Microscopy Probe for Cervical Precancer

Launched by BRITISH COLUMBIA CANCER AGENCY · Oct 9, 2015

Keywords

ClinConnect Summary

All subjects will undergo standard management (colposcopy) for their cervical lesion as scheduled. For cervical sites suspicious of dysplasia, acriflavine hydrochloride 0.05% solution will be applied topically, then rinsed with saline prior to in vivo confocal imaging with the hand-held probe. Following that, a biopsy of the suspicious site will be performed irrespective of the confocal microscopy finding. A biopsy of the normal site will be taken for research purposes. The confocal probe imaging will not alter where and how the biopsies will be taken (no change to size of biopsy or locatio...

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • indicate understanding of the study
• • provide informed consent to participate
• • 18 years old or older
• • not pregnant and have negative urine pregnancy test
• • be schedule for colposcopy \& biopsy at the Vancouver General Hospital Women's Clinic
• Exclusion Criteria:
• • they are breast-feeding
• • they had an operation to remove their cervix