Assessment of the Impact of a Coenzyme Q10 Supplementation on the Skin

Launched by VIST - FACULTY OF APPLIED SCIENCES · Nov 11, 2015

Keywords

ClinConnect Summary

Objective of the study is to determine the influence of dietary supplementation of CoQ10 in form of water-soluble Q10vital® on skin conditions. 33 healthy female subjects will be randomly assigned to a placebo group, a low-dose (LD) group receiving 50 mg CoQ10/day and a high-dose group (HD) receiving 150 mg CoQ10/day (11 subjects per group). A water-soluble form of CoQ10 with improved bioavailability (Quvital syrup with Q10vital®, Valens Int. d.o.o., Slovenia) will be used. The placebo or CoQ10 will be administered in the form of a syrup; all subjects will consume 5 mL of syrup daily for 12...

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Signs of skin aging (mimic wrinkles/ poor skin tone/ visual dryness),
• • Photoaged skin on the face,
• • Expression of mimic wrinkles,
• • Phototype II and III.
• Exclusion Criteria:
• • Allergy to ingredients of tested products
• • High blood cholesterol and use of cholesterol-lowering medicines,
• • Diagnosed diabetes
• • Thyroid disease
• • Inflammatory skin diseases,
• • Regular use of dietary supplements 6 months or less before start of the study,
• • Invasive rejuvenation treatments (botox injections, hyaluronic acid fillers, needle rollers, needle mesotherapy, etc.) 6 months or less prior to start of the study,
• • Non-invasive rejuvenation treatments (radiofrequency, electrotherapy, ultrasound therapy, no-needle mesotherapy, etc.) 6 months or less prior to start of the study,
• • The use of cosmetic products containing coenzyme Q10 6 months or less prior to start of the study,
• • Gluteal hyperpigmentation,
• • Expected sunbathing (also in solariums) within the study period.