Evaluation of Virtual Touch Tissue Imaging Quantification (VTIQ - 2D-SWE) in the Assessment of BI-RADS® 3 and 4 Lesions

Launched by HEIDELBERG UNIVERSITY · Dec 18, 2015

Keywords

ClinConnect Summary

Elastography is a method of imaging tissue stiffness. It is based on shear wave velocity information that can be mapped to create an image of the stiffness in the region of interest.

Sonoelastography is used to differentiate benign from malignant lesions since malignant lesions alter tissue elasticity.

Adding Shear Wave elastographic features to BI-RADS® feature analysis- especially in lesions scored BI-RADS® 3 and 4a- improved specificity of breast US mass assessment without loss of sensitivity.

The BI-RADS® categories are defined by the risk for a malignant lesion varying from benign B...

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Female
• • Age ≥18 years
• • Patients with a lesion ≥ 0.5 cm in largest diameter size, initially scored BI-RADS® 3, 4a, 4b or 4c in B-mode ultrasound
• • Informed consent about histological examination (core cut biopsy (CCB), vacuum-assisted biopsy (VAB), fine needle aspiration (FNA) or surgery) has already been given in the course of clinical routine
• • Signed informed consent of study participation
• Exclusion Criteria:
• • Pregnant or lactating women
• • Women with breast implants on the same side as the lesion
• • Women that underwent local radiation or chemotherapy within the last 12 months
• • Women with history of breast cancer or breast surgery in the same quadrant
• • Lesions in or close to scar tissue (\< 1cm)
• • Skin lesions or lesions that have been biopsied previously
• • Lesion larger than 4 cm in the longest dimension
• • No lesion should be included when more than 50% of the lesion is further down than 4 cm beneath the skin level.