Pre-operative Carbohydrate Drink to Preserve Peri-operative Insulin Sensitivity

Launched by MCGILL UNIVERSITY HEALTH CENTRE/RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE · Feb 3, 2016

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Gender

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Eligibility criteria

• Inclusion Criteria:
• • 1. At least 18 years of age
• • 2. Planned laparoscopic partial colon resection for non-metastatic neoplastic or benign disease (including right, transverse, left or sigmoid))
• • 3. HbA1c less than or equal to 5.7%
• • 4. Not receiving any kind of glucose lowering medication.
• Exclusion Criteria:
• • 1. Are already diagnosed with diabetes or pre diabetes (HbA1c \> 5.7%)
• • 2. Are pre-diabetic receiving glucose lowering intervention (any glucose lowering medication)
• • 3. Have renal or liver dysfunction (serum creatinine above 1.4 mg/dL in women and 1.5 mg/dL in men, bilirubin \>2.9 mg/dL)
• • 4. Will undergo extended resection of adjacent organs
• • 5. Non-elective operations
• • 6. New stoma created
• • 7. Have conditions precluding participation in the ERAS pathway (e.g. dementia, disabling orthopedic and neuromuscular disease, psychosis)
• • 8. Have conditions requiring preoperative fasting: documented gastroparesis, patient on metoclopramide and/or domperidone, achalasia, dysphagia (any difficulty with swallowing), or Fluid restriction (e.g. dialysis, pulmonary oedema, congestive heart failure).
• • 9. Have cardiac abnormalities, severe end-organ disease such as cardiac failure (New York Heart Association classes III-IV), chronic obstructive pulmonary disease (documented by abnormal pulmonary function test), morbid obesity (BMI \>40 kg/m2), anemia (hematocrit \< 30 %, hemoglobin \<100g/L, albumin \< 25mg/dl)
• • 10. Have received steroids for longer than 30 days
• • 11. Have poor English or French comprehension.