Screening for Congenital Cytomegalovirus Infection in Newborns

Launched by SOUTHERN ILLINOIS UNIVERSITY · Feb 11, 2016

Keywords

ClinConnect Summary

Congenital cytomegalovirus (CMV) infection is the leading non-genetic cause of sensorineural hearing loss (SNHL) in children in the United States, and is the most frequent known viral cause of mental disability. Approximately one percent of all newborn infants in the United States are infected with CMV. Of those infected, approximately 10% have involvement that is evident at birth (symptomatic congenital CMV disease) with manifestations including microcephaly, central nervous system abnormalities, chorioretinitis, hepatosplenomegaly, and SNHL. The most common sequelae following congenital C...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Viable Infants with a failed hearing screen or a diagnosis of SGA who are born at either St. John's Hospital or MMC at ≥ 28 weeks gestation.
• Exclusion Criteria:
• • Infants born ≤ 27 weeks gestation, infants who are not SGA, infants who pass their newborn hearing screen.