Glyceryl Trinitrate Ointment vs Posterior Tibial Nerve Stimulation in the Treatment of Anal Fissure
Launched by HOSPITAL GENERAL UNIVERSITARIO ELCHE · Mar 1, 2016
Trial Information
Current as of May 21, 2025
Completed
Keywords
ClinConnect Summary
Patients were randomly assigned to experimental and control groups: those patients undergoing PPTNS (Experimental Group - EG) and those receiving glyceryl trinitrate ointment (Control Group - CG).
Treatments:
Glyceryl trinitrate ointment (GTO): Commercially available aluminium tubes containing 0.4 glyceryl trinitrate ointment (Rectogesic, proStrakan Group, Galashiels, UK) were purchased from pharmacies. The dosage for all the patients was 375 mg of ointment (containing 1.5 mg of glyceryl trinitrate), applied with a gloved finger to the distal anal canal, every 12 hours for an 8-week perio...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • persistent anal fissure after the failure of hygienic and dietary measures over at least a 6-week period
- Exclusion Criteria:
- • associated anal pathologies
- • intestinal inflammation disorders
- • fissures secondary to underlying diseases
- • patients with previous history of headaches
About Hospital General Universitario Elche
Hospital General Universitario Elche is a leading healthcare institution dedicated to providing high-quality medical services and advancing clinical research. Located in Elche, Spain, the hospital is committed to improving patient outcomes through innovative studies and trials across various medical disciplines. With a multidisciplinary team of experienced healthcare professionals, the hospital fosters a collaborative environment that prioritizes patient safety and ethical standards. Its active involvement in clinical trials not only contributes to the advancement of medical knowledge but also enhances the standard of care available to the community.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Trial Officials
Eduardo Barna, MD, PhD
Study Chair
Garcilaso Clinic
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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