Surgical Conditions During Laparoscopic Bariatric Surgery

Launched by UNIVERSITY OF MISSOURI-COLUMBIA · Mar 8, 2016

Keywords

ClinConnect Summary

Subjects will be randomized to one of four groups:

1. moderate neuromuscular block (NMB) + 10 mm insufflation pressure (IP);
2. moderate NMB + 15 mm IP;
3. deep NMB + 10 mm IP; or
4. deep NMB + 15 mm IP.

A moderate NMB block will be defined as 2-3 twitches in the train of four (TOF) and a deep NMB will be defined as 0-1 posttetanic count. The surgeons will be asked to rate their satisfaction with the surgical conditions using a five-point ordinal scale ranging from 1 (extremely poor) to 5 (optimal conditions). The first rating will occur at the beginning of the procedure when the NMB leve...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥ 18 years
• • ASA I-III
• • BMI ≥ 35
• Exclusion Criteria:
• • Inability to obtain written informed consent
• • Pregnancy or breastfeeding
• • Allergy to rocuronium, sugammadex, or any anesthetic agents used in the protocol
• • Known or suspected neuromuscular disorders
• • Significant renal disease with a serum creatinine ≥ 2 mg/dl f. Significant liver disease g. A family history of malignant hyperthermia