Nitric Oxide Donors for Treatment of Isolated Oligohydramnios

Launched by BENHA UNIVERSITY · Mar 14, 2016

Keywords

ClinConnect Summary

This prospective randomized interventional study was done in Obstetrics and Gynecology Department , Benha University Hospital, Alkalubia, Egypt from August 2013 to August 2015.

The study protocol was approved by the Local Ethics Committee and written informed consents were taken from patients entering the study. The study included 100 women aged 18-35 years with singleton pregnancy about 28-36 weeks gestation, with diagnosed isolated oligohydramnios (AFI less than 5 cm).

Initially, all the participants were subjected to through routine antenatal history taking and examination and by routi...

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Singleton pregnancy
• • 28-36 weeks gestation,
• • Diagnosed isolated oligohydramnios (AFI less than 5 cm).
• Exclusion Criteria:
• • Multiple pregnancy;
• • Fetal chromosomal or congenital abnormalities;
• • Signs of fetal distress;
• • Preterm rupture of membranes;
• • Intrauterine infection;
• • Receiving treatment for oligohydramnios ;
• • History of maternal heart disease;
• • Vasodilator use; sensitivity to NO donors ;
• • Pre-existing chronic medical problems.