Effect of B-GOS on the Wellbeing and Ageing in Healthy 52-65 Years Old Individuals

Launched by CLASADO LIMITED · Mar 17, 2016

Keywords

ClinConnect Summary

With age, several important alterations occur within the gastrointestinal (GI) tract, that are responsible for altered microbial environment (e.g. reduced diversity and number of beneficial bifidobacteria and higher populations of enterobacteria and clostridia).

Research over the past two decades has provided evidence that administration of probiotics (live microorganisms which, when administered in adequate amounts, confer a health benefit on the host) could be used to optimise gut microbiota and prevent and treat a range of diseases, as well as enhance immune function. Somewhat less docu...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Aged between 52 and 65 years of age
• • In good general health, defined as no comorbidities requiring regular medical follow up
• • Ability to communicate well with the investigator and to comply with the requirements of the entire study
• • The volunteer has given written informed consent to participate and is willing to participate in the entire study
• Exclusion Criteria:
• • History or evidence of organic disease of the gastrointestinal tract; such as tumour, irritable bowel syndrome, etc., within the previous 5 years
• • Consumed probiotic or prebiotic preparations on a regular basis (at least 3 times per week) in the last 2 weeks and during the trial period
• • Former participation in another study involving prebiotic or probiotic preparations or investigational drugs within the previous 6 months, or intention to use such drugs during the course of the study
• • Undergone surgical resection of any part of the bowel
• • History of malignancy within the previous 5 years (with exception of well-treated basal cell carcinoma or in situ cervical carcinoma).
• • Currently prescribed immunosuppressive drugs
• • Intention to use regularly other medication which affects gastrointestinal motility and/or perception
• • Current or recent history (within 12 months) of significant drug or alcohol abuse or dependence