Reconstruction Techniques and Vascular Approach After Laparoscopic Left Hemicolectomy and Rectum Low Anterior Resection

Launched by INSTITUT D'INVESTIGACIÓ BIOMÈDICA DE GIRONA DR. JOSEP TRUETA · Apr 18, 2016

Keywords

ClinConnect Summary

This is an interventional, controlled and randomized single-center clinical trial with patients diagnosed with colorectal cancer that will undergo laparoscopic left hemicolectomy or laparoscopic low anterior resection for rectal cancer.

Methods:

All patients included in the study (study 1) are randomized into two groups (group 1A and group 1B): in the group 1A the surgical technique initially dissects the inferior mesenteric vein (IMV) and in the group 1B the surgical technique initially dissects the inferior mesenteric artery.

The patients who will undergo a colorectal anastomosis will ...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• Study 1:
• • Patients with colorectal cancer that will undergo laparoscopic left hemicolectomy or laparoscopic low anterior resection for rectal cancer.
• • Age ≥ 18 years
• • Histology proven adenocarcinoma or adenoma with or without chemotherapy or neoadjuvant radiochemotherapy
• • Any T, any N, M or any adenoma
• • Attempt to R0 resection
• • Signed informed consent by the patient and by the researcher
• • Quality of Life Questionnaire completed
• Study 2:
• • Patients with colorectal cancer that will undergo laparoscopic left hemicolectomy or laparoscopic low anterior resection for rectal cancer with colorectal anastomosis.
• • Age ≥ 18 years
• • Histology proven adenocarcinoma or adenoma with or without chemotherapy or neoadjuvant radiochemotherapy
• • Any T, any N, M or any adenoma
• • Attempt to R0 resection
• • Signed informed consent by the patient and by the researcher
• • Quality of Life Questionnaire completed
• Exclusion Criteria:
• Study 1:
• • Colorectal tumor with different histology to adenocarcinoma or adenoma
• • History of colorectal cancer surgery different to the local excision
• • Inflammatory bowel disease with pathologic confirmation
• • Patients with psychiatric illness, addiction or disorder with inability to understand informed consent
• • Inability to read or understand any of the languages of the informed consent and questionnaires (Catalan, spanish)
• • Another synchronous malignancy
• • Emergency Surgery
• • Any patient that medical characteristics present an individual risk raised to be included and complete the study
• Study 2:
• • Patients who won't undergo colorectal anastomosis
• • Colorectal tumor with different histology to adenocarcinoma or adenoma
• • History of colorectal cancer surgery different to the local excision
• • Inflammatory bowel disease with pathologic confirmation
• • Patients with psychiatric illness, addiction or disorder with inability to understand informed consent
• • Inability to read or understand any of the languages of the informed consent and questionnaires (Catalan, spanish)
• • Another synchronous malignancy
• • Emergency Surgery