The London COPD Exacerbation Cohort

Launched by IMPERIAL COLLEGE LONDON · Apr 26, 2016

Keywords

ClinConnect Summary

The London COPD Exacerbation Cohort, also known as the EXCEL study, is researching chronic obstructive pulmonary disease (COPD) and how it affects people’s health over time. This study aims to better understand COPD flare-ups, which can make breathing harder and worsen overall health. It builds on a previous study that began in 1995, and researchers are currently looking for new participants to join.

To be eligible for this study, you should be between 14 and 36 years old and have a specific measure of lung function that shows you have COPD. You need to be able to give informed consent, meaning you understand what the study involves and agree to participate. However, if you have a history of asthma, certain lung diseases, or are currently taking certain medications like long-term steroids or immunosuppressants, you won't be able to join. If you decide to participate, you'll help researchers learn more about COPD and contribute to improving treatments for this condition.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Forced Expiratory Volume in 1 sec (FEV1)/Forced Vital Capacity (FVC) ratio of \<0.70
• • Able and willing to give informed and written consent
• Exclusion Criteria:
• • Patients with a history of asthma, bronchiectasis, carcinoma of the bronchus, or other significant respiratory disease were excluded.
• • Patients on Immunosuppressive medications or with active cancer
• • Long term steroid therapy
• • Age \<40 years at recruitment

Trial Officials