Hypofractionated Image-Guided Radiotherapy (IGRT) With Organ Motion Mitigation and Urethral Sparing for Prostate Cancer

Launched by FUNDACAO CHAMPALIMAUD · May 2, 2016

Keywords

ClinConnect Summary

No description provided

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • Signed study specific informed consent form;
• • Histologic confirmation of adenocarcinoma of the prostate by biopsy;
• • Previous hormonal therapy is allowed (but not required);
• • No direct evidence of regional or distant metastases after appropriate staging studies;
• • Age ≥ 40;
• • Performance Status 0-2;
• • American Urological Association (AUA) score must be ≤ 20 (alpha blockers allowed);
• • Computerized Tomography (CT) or Ultrasound-based volume estimation of prostate gland ≤ 150 grams.
• Exclusion Criteria:
• • Metastatic disease from prostate cancer on imaging studies MRI evidence of radiographic T3, T4;
• • Previous pelvic radiotherapy;
• • Previous surgery for prostate cancer;
• • Previous hormonal therapy given for more than 6 months prior to therapy;
• • History of Crohn's Disease or Ulcerative Colitis;
• • Previous significant obstructive symptoms;
• • Significant psychiatric illness;
• • Severe, active co-morbidity as defined in section 3.