Using Cardiac MRI to Characterise the Dynamic Changes Which Occur in the Acutely Reperfused STEMI Patient

Launched by NATIONAL HEART CENTRE SINGAPORE · May 31, 2016

Keywords

ClinConnect Summary

This will be a prospective observational study with serial CMR imaging only.

CMR scan Each patient will receive one CMR scan performed on Day 1, Day 3, Day 5, Day 10 following the PPCI procedure on a 3T Philips scanner (see study flow below). All CMR scans will be analysed at a central CMR corelab.

For Day 1, 3, 5, 7 and 10 CMRs, parameters will be collected as follows:

* Left ventricle (LV) ejection fraction and indexed LV end systolic and diastolic volumes and mass using short-axis SSFP cine imaging and myocardial tagging sequences).
* The AAR by T1 and T2 mapping18 as a percentage of ...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Confirmed STEMI as per PPCI procedure reports/ clinical notes
• • 2. Proximal to mid coronary artery occlusion.
• • 3. Ability to provide informed consent
• Exclusion Criteria:
• • 1. Previous myocardial infarction or coronary artery bypass graft surgery
• • 2. Contraindication for CMR (e.g. ferromagnetic implants, claustrophobia, estimated glomerular filtration rate \<30mL/min)