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The Use of MRI in the Assessment of Suspected Scaphoid Fracture With Negative Findings on the Initial Plain Radiography

Launched by GUY'S AND ST THOMAS' NHS FOUNDATION TRUST · Jun 14, 2016

Trial Information

Current as of May 08, 2025

Unknown status

Keywords

ClinConnect Summary

The scaphoid bone is an obliquely orientated bone on the radial (thumb) side of the wrist, between the distal carpal row and the radius. Wrist injury is a common presentation to the Emergency Department (ED) in the UK. Amongst these patients, the scaphoid is the most commonly fractured carpal bone, accounting for 51-90% of carpal fractures and between 2-7% of all fractures.

Given that: 1) various clinical complications may arise from a misdiagnosed scaphoid fracture; and 2) clinical and radiographic diagnosis of scaphoid fracture is often challenging, particularly at the time of presentati...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Every patient aged 16 years or over presenting at A\&E/UCC with clinical history and examination consistent with a suspected scaphoid fracture but negative findings on the initial 4-view plain x-ray. It is considered that a patient has suspected scaphoid fracture if at least one of the following criteria are present:
  • Isolated pain / tenderness over the Anatomical Snuff Box (ASB) or Scaphoid Tubercle or pain in the scaphoid region during axial loading of the 1st metacarpal.
  • History of recent fall (\< 14 days) on an out-stretched hand (FOOSH), wrist injury or poor history associated with examination findings suggestive of scaphoid fracture.
  • Furthermore, only patients that present at A\&E/UCC during the following schedule of MRI normal working hours will be included in the study:
  • Patients screened for the study at A\&E/UCC on weekdays after 7.30 am and before 6 pm;
  • Patients screened for the study at A\&E/UCC on weekends or Bank Holidays after 9 am and before 4 pm.
  • Exclusion Criteria:
  • Patients presenting outside GSTT's catchment area who are not willing to be followed-up at GSTT;
  • Patients with a confirmed scaphoid fracture following the initial 4-view plain x-ray;
  • Patients with confirmed ipsilateral upper limb injury/injuries (e.g. wrist/forearm/arm injury) following initial conventional x-ray examination(s) - regardless of the findings around the suspected scaphoid fracture.
  • Patients with suspected scaphoid fracture not admitted through A\&E at St Thomas' Hospital or Urgent Care Centre (UCC) at Guy's Hospital;
  • Patients who lack capacity to give consent or participate in the study;
  • Patients that are already taking part in a Clinical Trial of an Investigational Medicinal Product (CTIMP);
  • Prisoners.

About Guy's And St Thomas' Nhs Foundation Trust

Guy's and St Thomas' NHS Foundation Trust is a leading healthcare organization in the United Kingdom, renowned for its commitment to delivering high-quality patient care, innovative research, and clinical excellence. As a prominent academic health science center, the Trust integrates cutting-edge research with clinical practice, facilitating the translation of scientific discoveries into improved treatment options. With a diverse portfolio of clinical trials across various medical specialties, Guy's and St Thomas' NHS Foundation Trust plays a pivotal role in advancing healthcare knowledge and enhancing patient outcomes, while maintaining the highest ethical standards in research and patient safety.

Locations

London, , United Kingdom

Patients applied

0 patients applied

Trial Officials

Sam Gidwani

Principal Investigator

Guy's and St Thomas' NHS Foundation Trust

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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