Regenerative Endodontic Procedure of Immature Permanent Teeth With Apical Periodontitis Using PRF
Launched by FUJIAN MEDICAL UNIVERSITY · Jun 12, 2016
Trial Information
Current as of June 01, 2025
Completed
Keywords
ClinConnect Summary
The conventional method of regenerative endodontic procedure using a blood clot as scaffold materials has shown successful results. However, it is very difficult to induce bleeding and place mineral trioxide aggregate over a blood clot. Platelet-rich fibrin (PRF), a second-generation platelet concentrate. PRF is a matrix of autologous fibrin containing a large quantity of platelets, growth factors and leukocytes. PRF preparation technique is very simple, inexpensive and doesn't require any chemical agents. The purpose of this study is to test the hypothesis that the use of PRF in regenerati...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Between 6 and 18 years of age
- • Provision of Informed Consent
- • Cooperative in the dental chair
- • Permanent immature teeth with apical periodontitis and incomplete root development
- Exclusion Criteria:
- • Have a medical history that may complicate treatment
- • Unlikely to be able to comply with the study procedures
About Fujian Medical University
Fujian Medical University is a prestigious academic institution located in Fujian Province, China, dedicated to advancing medical education, research, and clinical practice. With a strong emphasis on innovative healthcare solutions, the university actively engages in clinical trials to explore new therapeutic interventions and improve patient outcomes. Its comprehensive research programs are supported by a team of experienced professionals and state-of-the-art facilities, enabling the university to contribute significantly to the global medical community. Through its commitment to excellence and collaboration, Fujian Medical University aims to enhance the quality of healthcare delivery both locally and internationally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Fuzhou, Fujian, China
Patients applied
Trial Officials
Xiaojing Huang, PhD
Study Chair
School and Hospital of Stomatology, Fujian Medical University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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