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Search / Trial NCT02832570

Sildenafil Efficacy Study on Time Walk From Peripheral Arterial Desease Patients (Stade II) With Arterial Claudication

Launched by UNIVERSITY HOSPITAL, ANGERS · Jul 12, 2016

Trial Information

Current as of June 04, 2025

Completed

Keywords

ClinConnect Summary

Sildenafil 100mg or Placebo Oral intake 2 hours before the treadmill test Safety and security control throughout the period of drug efficacy (approx 4 hours) Evaluation of maximal walking distance for a constant load treadmill test (3.2 kml/h 10% slope)

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patient with peripheral arterial desease stade II
  • Patient with vascular claudication for at least 3 months
  • Patient able to perform a treadmill walking test with time to walk \< 5min
  • Exclusion Criteria:
  • Patient suffering from ischemia
  • Previous angina or myocardial
  • Patient treated with nitrates drugs
  • Patient with severe renal insufficiency
  • Patient with severe hepatic insufficiency
  • Patient with hypotension

About University Hospital, Angers

The University Hospital of Angers is a leading academic medical institution dedicated to advancing healthcare through innovative research and clinical trials. As a prominent sponsor of clinical studies, the hospital leverages its multidisciplinary expertise and state-of-the-art facilities to investigate new therapeutic approaches and improve patient outcomes. Committed to excellence in patient care and medical education, the University Hospital of Angers collaborates with a network of researchers and healthcare professionals to facilitate groundbreaking studies across various medical fields, ensuring rigorous adherence to ethical standards and regulatory compliance. Through its clinical trial initiatives, the institution aims to contribute significantly to the advancement of medical knowledge and the development of effective treatments.

Locations

Patients applied

0 patients applied

Trial Officials

Loukman OMARJEE, MD

Principal Investigator

University Hospital, Angers

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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