Cohort Biomonitoring Study to Evaluate the Biocompatibilty of Resin-based Dental Materials

Launched by UNIVERSITAIRE ZIEKENHUIZEN KU LEUVEN · Aug 17, 2016

Keywords

ClinConnect Summary

This clinical trial is looking at the safety of certain dental materials used for fillings and other restorations in adults. Researchers want to understand how these materials may affect the body, specifically by measuring levels of a chemical called bisphenol A (BPA) in urine and saliva, and by examining changes in DNA. The study will include adults aged 65 to 74, and they will take samples from participants at different times to gather information.

To participate, individuals need to be Caucasian adults without serious health issues, recent oral infections, or conditions that require ongoing medication. Participants can expect to provide urine, saliva, and cheek cell samples, which will be analyzed to assess the impact of the dental materials on their health. It's important to note that those who smoke, drink alcohol, or have had X-rays in the last two months will not be eligible for this study.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Caucasian, adults,
• Exclusion Criteria:
• • acute or chronic medical condition, presence of oral inflammatory conditions during the previous 2 weeks, chronic disease requiring intake of drugs, exposure to diagnostic X-rays in the previous 2 months, smoking and consumption of alcohol