Early PKD Observational Cohort Study

Launched by UNIVERSITY OF KANSAS MEDICAL CENTER · Oct 17, 2016

Keywords

ClinConnect Summary

The Early PKD Observational Cohort Study is a research project designed to better understand polycystic kidney disease (PKD) in its early stages. Researchers will collect blood and urine samples, along with health information, from individuals with early-stage PKD, their siblings who do not have the disease, and healthy volunteers. The goal of this study is to identify biological markers, known as biomarkers, that could help track how the disease progresses. This information can be crucial for developing new treatments for PKD patients in the future.

To participate, individuals with early-stage autosomal dominant PKD must have a family history of the disease and a specific level of kidney function. Healthy volunteers can also join if they have no family history of kidney disease. Participants can expect to provide samples and health information and may undergo imaging tests like MRI. This study is currently recruiting participants of all ages and backgrounds, and your involvement could contribute to important advancements in understanding and treating PKD.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• * Inclusion for early stage autosomal dominant polycystic kidney disease (ADPKD):
• • Family history of PKD
• • All races and ethnic groups
• • Glomerular filtration rate (GFR) \>80 ml/min per 1.73 m2
• * Inclusion for Healthy Volunteers:
• • Male or female with no family history of kidney disease
• • All races and ethnic groups
• • Normal GFR
• Exclusion Criteria:
• • Non-insulin or insulin-dependent diabetes mellitus
• • Systemic illness (i.e.systemic lupus erythematosus, vasculitis)
• • Unable to provide written informed consent
• • Unavailable for magnetic resonance imaging (MRI) and blood/urine collection