Potassium Oxalate and Potassium Nitrate and Post-bleaching Sensitivity
Launched by UNIVERSIDADE FEDERAL DE SERGIPE · Oct 20, 2016
Trial Information
Current as of June 04, 2025
Completed
Keywords
ClinConnect Summary
Methods \& Materials:
This clinical trial was approved by the Scientific Review Committee and by the Committee for the Protection of Human Subjects of the local university (CAAE 60259316.2.0000.5546).
Trial design:
This study will be a randomized, triple-blinded, placebo-controlled clinical trial, and split mouth study design.
The patients included will be submitted to two in-office bleaching sessions receiving the potassium nitrate 2% and postassium oxalate 5% desensitivity gel application on vestibular surface, for 10 minutes. A delay of 1 week between the sessions will be established...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients included in this clinical trial will be at least 18 years old with good oral health;
- • Patients presenting all six upper anterior teeth with shade mismatching with 2.5 M2 (Vita Bleachguide 3D-Master scale, Vita-Zahnfabrik, Bad Sackingen, Germany) or darker will be included.
- Exclusion Criteria:
- • Patients with any of the six upper anterior teeth with caries;
- • Restorations in anterior teeth'
- • Patients with tooth severe discoloration (e.g., stains caused by tetracycline);
- • Presence of enamel hypoplasia;
- • Presence of gingival recession or dentin exposure;
- • Presence of tooth pulpitis or endodontics;
- • Participants submitted to previous bleaching procedures;
- • Patients with prior tooth sensitivity;
- • Patients with known allergy to any component of medication used in the study;
- • Pregnant or breastfeeding will also be also excluded.
About Universidade Federal De Sergipe
The Universidade Federal de Sergipe (UFS) is a prominent public educational institution in Brazil, dedicated to advancing research and innovation in the health sciences. As a clinical trial sponsor, UFS is committed to conducting high-quality research that adheres to ethical standards and regulatory requirements. The university's diverse team of researchers and healthcare professionals collaborates to explore new treatments and interventions, aiming to improve patient outcomes and contribute valuable knowledge to the scientific community. UFS emphasizes a multidisciplinary approach, fostering partnerships with national and international institutions to enhance the impact and reach of its clinical studies.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Aracaju, Sergipe, Brazil
Patients applied
Trial Officials
Flavia Pardo S Nahsan, PhD
Principal Investigator
Universidade Federal de Sergipe
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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