Ostearthritis Biomarkers and Rehabilitation

Launched by HOSPITAL ISRAELITA ALBERT EINSTEIN · Nov 11, 2016

Keywords

ClinConnect Summary

Detailed Description:

Methods/Design

1. Participants after being textually and verbally informed about their rights, benefits and possible risks, objectives and methodologies of this study, all participants will sign a free and informed consent form.
2. Study Design Prior to the rehabilitation protocol (RP), participants will perform one adaptation session to all the functional tests that will be applied to minimize learning bias. In the second session after 5 minutes warm up in a cycle ergometer (CEE), the Time Up and Go (TUG) test will be applied, followed by the isometric strength test...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Women and men aged 45-65 years
• • Clinical knee osteoarthritis according to the American College of Rheumatology Clinical Criteria
• • Kellgren and Lawrence (KL) radiographic osteoarthritis grade 2 and 3 (mild to moderate radiographic osteoarthritis)
• Exclusion Criteria:
• • Severe knee osteoarthritis according to the KL classification (grade 4)
• • Other known major musculoskeletal impairments in the lower extremities or the back or prostheses in any joint of the lower extremities
• • Known serious coronary heart diseases or cancer
• • Body mass index \>35
• • Scheduled for surgery in any joint
• • Persons who already perform sports related moderate physical activity more than two times a week
• • History of knee replacement surgery or high tibial osteotomy;
• • Any knee surgery or corticosteroid injections within the previous 6 months;
• • Miss more than two rehabilitation sessions during the program or more than two consecutive sessions.