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Search / Trial NCT02973295

Silymarin in NAFLD

Launched by UNIVERSITY HOSPITAL RIJEKA · Nov 21, 2016

Trial Information

Current as of May 23, 2025

Withdrawn

Keywords

Nafld; Fibroscan Silymarin

ClinConnect Summary

In this study will participate patients who come to the regular ambulatory examinations (referred by gastroenterologists, nephrologists or family physicians in the Department of Gastroenterology and Department of Nephrology, dialysis and kidney transplantation KBC Rijeka) and have one or more components of the metabolic syndrome (hypertension, diabetes, obesity, dyslipidemia).Nonalcoholic fatty liver disease will be defined by transient elastography (FibroScan, Echosens, Paris); Controlled Attenuation Parameter (CAP) for assesment of liver steatosis and Liver Stiffness Measurements (LSM) fo...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • NAFLD patients
  • signed informed consent
  • possibility to follow instruction and the protocol
  • Exclusion Criteria:
  • chronic B or C hepatitis
  • usage of hepatotoxic drugs in the period of 6 months before inclusion
  • chronic kidney insufficiency (grade 4 and 5), hemodialysis
  • any other chronic liver disease
  • opioid dependancy
  • any malignancy
  • HIV seropositivity
  • alcohol abuse
  • pregnancy
  • inability to follow the protocol

About University Hospital Rijeka

University Hospital Rijeka is a leading healthcare institution in Croatia, dedicated to advancing medical research and patient care. With a commitment to scientific innovation and clinical excellence, the hospital serves as a prominent sponsor of clinical trials, facilitating the development of new therapies and treatments across various medical disciplines. The institution leverages its multidisciplinary expertise and state-of-the-art facilities to conduct rigorous research, ensuring adherence to ethical standards and regulatory compliance. Through collaboration with academic partners and industry stakeholders, University Hospital Rijeka aims to enhance health outcomes and contribute to the global body of medical knowledge.

Locations

Rijeka, Kresimirova 42, Croatia

Patients applied

0 patients applied

Trial Officials

Goran Hauser, MD, PhD

Principal Investigator

Clinical Hospital Centre Rijek, Croatia

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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