The Cognitive Resilience Study
Launched by DUKE UNIVERSITY · Jan 9, 2017
Trial Information
Current as of June 07, 2025
Completed
Keywords
ClinConnect Summary
The objective is to establish the feasibility and evaluate the role of two novel tests of cognitive resilience for use in identification of early Alzheimer's Disease. The investigators hypothesize that exposure to the controlled stressor of increased cognitive task demand will evoke measurable phenotypes of poor resilience, which will be associated with Alzheimer's Disease risk. The study will include 30 volunteer participants from the Duke Alzheimer's Disease Prevention Registry (ADPR). The ADPR cohort has been characterized according to genetic risk based on genotype at loci associated wi...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Able to walk 2 minutes without assistive device or assistance from another person
- • Cognitive function within normal limits
- Exclusion Criteria:
- • Unable to undergo MRI
- • Left handed
- • Red/Green Color Blind
- • Severe vision impairments
- • Diagnosis of Alzheimer's Disease or other dementia/memory problem
About Duke University
Duke University, a leading academic and research institution located in Durham, North Carolina, is renowned for its commitment to advancing healthcare through innovative clinical research. With a strong emphasis on interdisciplinary collaboration, Duke conducts a wide array of clinical trials aimed at developing cutting-edge therapies and improving patient outcomes across various medical fields. The university's Clinical Research Institute provides comprehensive support for trial design, implementation, and regulatory compliance, ensuring that all research adheres to the highest ethical and scientific standards. Duke’s dedication to translating research findings into effective clinical practices underscores its role as a pivotal contributor to the global medical community.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Durham, North Carolina, United States
Durham, North Carolina, United States
Patients applied
Trial Officials
Heather Whitson, MD, MHS
Principal Investigator
Duke University Aging Center
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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