Propionibacterium Acnes in Shoulder Arthroplasty

Launched by UNIVERSITY OF UTAH · Feb 15, 2017

Keywords

ClinConnect Summary

Over half of all post-operative infections after shoulder arthroplasty are due to Propionibacterium acnes. Even in apparently "aseptic" revisions, nearly all cultures taken at the time of revision surgery are positive for P acnes, and thus low-grade infection with this bacteria may be a more common cause of failure than previously suspected. Current antibiotic prophylaxis methods are ineffective against P acnes. Despite intravenous cefazolin, P acnes can be cultured from the glenohumeral joint in 42% of patients undergoing primary total shoulder arthroplasty. Despite skin preparation with c...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients undergoing primary shoulder arthroplasty
• Exclusion Criteria:
• • Patients with prior shoulder surgery.
• • Patients with a symptomatic infection or history of infection, recent antibiotic use (within six weeks), or with clinical signs of infection such as an elevated ESR, CRP, positive aspiration cultures, or positive biopsy.
• • Patients with a known hypersensitivity to hydrogen peroxide.