Comparison of the Effectiveness of Preemptive Paracetamol and Ibuprofen in Acute Postoperative Pain
Launched by ANKARA UNIVERSITY · Feb 23, 2017
Trial Information
Current as of May 08, 2025
Unknown status
Keywords
ClinConnect Summary
Laparoscopic cholecystectomy is a type of surgery that causes moderate postoperative pain. Paracetamol and non-steroid anti-inflammatory analgesics plus opioids are the mainstay treatment options of the moderate postoperative pain. These drugs are the most common used analgesics to ameliorate this type of pain and to reduce the consumption of opioids and their side effects.
Ibuprofen is a well-known anti-inflammatory drug and has been used as an oral formula for a long time. Few studies using its new intravenous formula had been conducted to evaluate its effectiveness for mixed type of sur...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. American Society of Anesthesiologist Functional Status 1-2
- • 2. Body mass index smaller than 30
- • 3. Undergoing laparoscopic cholecystectomy
- • 4. Age between 18-60 years
- Exclusion Criteria:
- • 1. Age under 18, above 60
- • 2. Weight under 40 kg
- • 3. Body mass index above 30
- • 4. Contraindication for opioid and non-steroid anti-inflammatory drug usage
- • 5. Allergy against paracetamol, opioids and anti-inflammatory drugs
- • 6. Peptic ulcer
- • 7. Tendency to bleeding
- • 8. Pregnancy or breast feeding
- • 9. Moderate or severe renal, hepatic or cardiac insufficiency
- • 10. Coronary artery disease
- • 11. Asthma
About Ankara University
Ankara University, a prominent institution in Turkey, is dedicated to advancing medical research and improving healthcare outcomes through innovative clinical trials. With a strong emphasis on scientific rigor and ethical standards, the university collaborates with various stakeholders to design and implement studies that address critical health challenges. Leveraging a diverse network of experienced researchers and state-of-the-art facilities, Ankara University aims to contribute significantly to the global medical community by generating valuable insights and fostering the development of effective therapeutic interventions.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Ankara, , Turkey
Ankara, , Turkey
Patients applied
Trial Officials
Zekeriyya Alanoglu, Professor
Principal Investigator
Ankara University Department of Anesthesiology and Intensive Care Medicine
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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