Cross-linked Hyaluronic Acid and Coenzyme Q10 in the Treatment of Dry Eye

Launched by AZIENDA OSPEDALIERA UNIVERSITARIA POLICLINICO "G. MARTINO" · Mar 7, 2017

Keywords

ClinConnect Summary

Introduction:

Dry eye disease (DED) is a common eye condition causing burden on visual function and reducing quality of life and work productivity. DED is a tear film disorder resulting in hyperosmolarity of tear film and inflammation of ocular surface that results in symptoms of discomfort, visual disturbance, and tear film instability with potential damage to the ocular surface. This condition provokes traumatisms caused by the movement of the eyelids on the ocular surface and an insufficient cleansing of the same by microbial agents and/or foreign bodies.

Prevalence of DED increases wi...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • age between 18 and 80 years,
• • history of at least 3 months of dry eye symptoms referable to mild to moderate dry eye.
• Exclusion Criteria:
• • presence of any ocular disease, present or past, other than dry eye;
• • previous ocular surgery,
• • use of contact lens or topic treatments other than tear substitutes;
• • presence of systemic diseases requiring a treatment with systemic drugs potentially interfering with tear productions;
• • hypersensitivity to the active substance or to excipients;
• • participation in a clinical trial during the 3 months prior to the beginning of the study,
• • pregnancy or breast-feeding.