Brown Seaweed Extract on Glycemic Control and Body Weight

Launched by LAVAL UNIVERSITY · Mar 6, 2017

Keywords

ClinConnect Summary

Diets that produce lower glucose and insulin responses may reduce diabetes and cardiovascular risk. They may also facilitate weight control by promoting satiety, insulin sensitivity and optimal insulin secretion after a meal. Food ingredients may indeed reduce postprandial glucose and insulin response through an inhibition of α-amylase and α-glucosidase activity that may slow down the absorption of carbohydrates. InSea2® is a unique combination of polyphenolic extracts of brown algae (Ascophyllum nodosum and Fucus vesiculosus) which has been shown to inhibit the action of α-amylase and α-gl...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • overweight (BMI \> 25; waist circumference ≥ 80cm for women and ≥ 94 cm for men)
• • fasting insulin (≥ 60 pmol/L)
• • Impaired fasting glycemia with or without impaired glucose tolerance
• • HbA1c between 5.6 and 6.4
• • non-smoking
• • stable weight in the past 3 months
• Exclusion Criteria:
• • diabetes
• • chronic disease (thyroid dysfunction, hepatic or gastrointestinal disorder, uncontrolled hypertension)
• • taking drugs that could affect glucose or lipid metabolism or weight and appetite
• • taking dietary supplements (protein powders, fish oil, omega-3 or any marine supplements) or natural health products that could affect glucose, lipid, weight or appetite
• • major surgery 3 months prior to the study
• • pregnancy
• • fish, seafood or iodine allergy