Evaluating Raised Intracranial Pressure Using MR Elastography
Launched by MAYO CLINIC · Mar 24, 2017
Trial Information
Current as of May 08, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying a new way to measure raised pressure inside the skull, a condition known as idiopathic intracranial hypertension. Researchers want to see how well a technique called MR elastography compares to other non-invasive methods, like looking at the eye's nerve fibers and using MRI scans, to detect this pressure increase. The goal is to find the best way to diagnose this condition, which can cause headaches and vision problems.
To participate in this study, you should be between 65 and 74 years old and have either symptoms of raised intracranial pressure, like swelling of the optic nerve (papilledema), or be someone without this condition for comparison. Unfortunately, people under 18, pregnant individuals, and those who cannot undergo MRI scans cannot participate. If you join, you can expect to undergo various tests to help researchers better understand how to detect this condition effectively. Your involvement could contribute to improving diagnosis and care for others with similar health issues.
Gender
ALL
Eligibility criteria
- All subjects will have the following inclusion criteria:
- • Group 1: Papilledema from idiopathic intracranial hypertension and other forms of elevated intracranial pressure, including obstructive hydrocephalus
- • Group 2: Patients without raised intracranial pressure.
- All subjects will have the following exclusion criteria:
- • Age \<18
- • Pregnancy (self-reported)
- • Individuals for whom MR is contraindicated
About Mayo Clinic
Mayo Clinic is a renowned nonprofit medical practice and research institution dedicated to providing comprehensive healthcare and advancing medical knowledge through innovative research and education. With a commitment to patient-centered care, Mayo Clinic conducts numerous clinical trials aimed at exploring new therapies and improving treatment outcomes across various disciplines. Leveraging a multidisciplinary approach, the institution collaborates with leading experts and cutting-edge technology to ensure rigorous scientific standards and ethical practices in all its research endeavors. Through its trials, Mayo Clinic seeks to translate breakthroughs in science into tangible benefits for patients, fostering advancements in medicine that enhance health and quality of life.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Rochester, Minnesota, United States
Patients applied
Trial Officials
John J Chen, M.D., Ph.D.
Principal Investigator
Mayo Clinic
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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