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Search / Trial NCT03120013

Rehabilitative Trial With Cerebello-Spinal tDCS in Neurodegenerative Ataxia

Launched by AZIENDA SOCIO SANITARIA TERRITORIALE DEGLI SPEDALI CIVILI DI BRESCIA · Apr 14, 2017

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Trial Information

Current as of April 24, 2025

Completed

Keywords

Transcranial Direct Current Stimulation Transcranial Magnetic Stimulation Spinocerebellar Ataxia Cerebellar Ataxia

ClinConnect Summary

Neurodegenerative cerebellar ataxias represent a heterogeneous group of disabling disorders in which progressive ataxia of gait, limb dysmetria, oculomotor deficits, dysarthria and kinetic tremor are the prominent clinical manifestations. Both the hereditary and sporadic forms usually present in young adulthood, and are characterized by atrophy of cerebellar or brainstem structures. Currently, cerebellar ataxia lack effective disease-modifying therapies.

Cerebellar transcranial direct current stimulation (tDCS) is a non-invasive technique, which has been demonstrated to modulate cerebellar...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • • Patients with a cerebellar syndrome and quantifiable cerebellar atrophy
  • Exclusion Criteria:
  • • Severe head trauma in the past
  • • History of seizures
  • • History of ischemic stroke or hemorrhage
  • • Pacemaker
  • • Metal implants in the head/neck region
  • • Severe comorbidity
  • • Intake of illegal drugs
  • • Pregnancy

Trial Officials

Barbara Borroni, MD

Principal Investigator

Azienda Ospedaliera Spedali Civili, Brescia

Alberto Benussi, MD

Principal Investigator

Università degli Studi di Brescia

About Azienda Socio Sanitaria Territoriale Degli Spedali Civili Di Brescia

The Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia is a leading healthcare organization based in Brescia, Italy, dedicated to providing high-quality medical services and promoting clinical research. As a prominent clinical trial sponsor, it focuses on advancing medical knowledge and improving patient care through innovative research initiatives. The institution integrates multidisciplinary expertise and state-of-the-art facilities to facilitate the development of new therapies and treatments, ensuring adherence to rigorous ethical and regulatory standards. With a commitment to enhancing public health, the Azienda plays a pivotal role in fostering collaborations among healthcare professionals, researchers, and industry partners.

Locations

Brescia, Bs, Italy

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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