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Search / Trial NCT03142607

Comparative Evaluation of Chlorhexidine, Metronidazole and Combination Gels on Gingivitis

Launched by AGA KHAN UNIVERSITY · May 4, 2017

Trial Information

Current as of June 18, 2025

Unknown status

Keywords

ClinConnect Summary

Training of the examiner:

Participating investigators(Resident and supervisor) will be trained and calibrated on the development of the trial, case selection, measurement techniques, sample collection, data compilation sheets and their precise role in the study. In order to evaluate the intra-examiner reliability, five subjects not involved in the study will be evaluated twice by each investigator for the measurements at the interval of one week.

Methodology:

On the first visit after clinical examination, the specially designed baseline study proforma will be filled-in. The bleeding site...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients having 20 or more healthy teeth
  • Systematically healthy patient with no co-morbid
  • Subjects with clinically confirmed gingivitis having positive bleeding gums on probing in every sextant
  • Subjects having teeth without any clinical attachment loss
  • Exclusion criteria:
  • Subjects with clinical attachment loss of greater than 2 mm on two sites
  • Pregnant or lactating females
  • Subjects with removal or fixed dental prosthesis
  • History of surgical or nonsurgical periodontal therapy in the last 6 months
  • Use of antibiotic in the last 30 days
  • Habit of smoking or use of smokeless tobacco
  • Allergic to Metronidazole or Chlorhexidine
  • Presence of any craniofacial syndrome patients
  • Patients on medications that have effects on gingival conditions (such as Nifedipine, Cyclosporine and Phenytoin etc.

About Aga Khan University

Aga Khan University (AKU) is a distinguished institution dedicated to improving health and education across developing regions. Established in 1983, AKU is recognized for its commitment to research excellence, particularly in clinical trials that address pressing health issues in diverse populations. With a focus on advancing medical knowledge and practice, AKU's clinical trial initiatives are designed to foster innovative solutions and enhance patient care. The university collaborates with various local and international partners, leveraging its multidisciplinary expertise to conduct rigorous research that informs public health policy and improves health outcomes in communities served by its facilities.

Locations

Karachi, Sindh, Pakistan

Patients applied

0 patients applied

Trial Officials

Robia Ghafoor, BDS, FCPS

Principal Investigator

Aga Khan University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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