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Search / Trial NCT03195816

A Computer-based Cognitive Stimulation in Mild Cognitive Impairment With White Matter Hyperintensities

Launched by LEILA DJABELKHIR · Jun 20, 2017

Trial Information

Current as of May 11, 2025

Unknown status

Keywords

Mild Cognitive Impairment White Matter Hyperintensities Computerized Cognitive Training Brain Plasticity

ClinConnect Summary

White matter hyperintensities (WMH) can appear in Mild Cognitive Impairment (MCI) and have been associated to executive, attention and processing speed deficits. Some findings indicate that the presence of WMH may contribute to Alzheimer's disease (AD) in addition to ß-amyloid, suggesting a greater vulnerability of MCI. One important challenge is to prevent or slowing down the progression of WMH. Few studies investigated the effects of computerized cognitive interventions in MCI with WMH, which deserve special attention. This study aim to investigate the effects of an intensive computer-bas...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Clinical diagnosis of Mild Cognitive Impairment
  • With and without with matter hyperintensities
  • MRI data available or accept to perform one
  • No engagement in other cognitive intervention program
  • Exclusion Criteria:
  • Psychiatric and neurological disorders
  • History of alcohol or other substance consumption
  • Sensory and or motor deficit that could interfere with the use of computer tool
  • Refusal MRI.

About Leila Djabelkhir

Leila Djabelkhir is a dedicated clinical trial sponsor known for her commitment to advancing medical research and improving patient outcomes. With a strong background in clinical development and regulatory affairs, she leads initiatives that focus on innovative therapies across various therapeutic areas. Her approach emphasizes collaboration with healthcare professionals, adherence to ethical standards, and the integration of patient perspectives in the research process. Through her leadership, Leila Djabelkhir aims to facilitate the successful transition of promising treatments from the research phase to clinical practice, ultimately contributing to the enhancement of global health.

Locations

Patients applied

0 patients applied

Trial Officials

Anne-Sophie AR RIGAUD, Professor

Principal Investigator

Broca University Hospital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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