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Search / Trial NCT03240354

Paediatric Microcuff Pressure Study

Launched by NOTTINGHAM UNIVERSITY HOSPITALS NHS TRUST · Aug 4, 2017

Trial Information

Current as of April 25, 2025

Completed

Keywords

ClinConnect Summary

During surgery under anaesthesia, use of cuffed endotracheal (ET) tubes is standard practice in adults. The cuff prevents air leak and protects the airway from soiling. Traditionally, in paediatric practice an uncuffed ET tube is used, sized according to the child's age. This prevents damage to the lining of the trachea by excessive pressure from the cuff.

The debate regarding the use of cuffed ET tubes in children is long-standing. New insight into the understanding of paediatric airway anatomy and newer designs of cuffed ET tubes (such as the MicroCuff Endotracheal tube, Halyard Health U...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Parent/guardian's written informed consent / age-appropriate participant assent
  • Age: Birth to 16 years
  • Elective surgery
  • Endotracheal intubation with a cuffed tube required as part of general anaesthesia lasting longer than 45 minutes
  • Planned use of N2O as part of balanced anaesthesia
  • For questionnaire follow up; aged over 8 years without significant neurological impairment
  • Exclusion Criteria:
  • Weight less than 3kg
  • Laryngeal or tracheal pathology, including respiratory tract infections
  • Difficulty in intubation (\>2 attempts)
  • NG tube placement during anaesthesia
  • Nose, throat or airway surgery

About Nottingham University Hospitals Nhs Trust

Nottingham University Hospitals NHS Trust is a leading healthcare provider in the UK, dedicated to delivering high-quality patient care and advancing medical research. Comprising two major hospitals, Queen's Medical Centre and Nottingham City Hospital, the Trust is at the forefront of clinical innovation and education. With a strong emphasis on translational research, Nottingham University Hospitals NHS Trust actively sponsors clinical trials aimed at improving treatment outcomes and understanding various health conditions. The Trust collaborates with academic institutions, healthcare professionals, and industry partners to foster a robust research environment that enhances clinical practice and contributes to evidence-based medicine.

Locations

Nottingham, Nottinghamshire, United Kingdom

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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