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Search / Trial NCT03242187

Trans-anal Versus Laparoscopic TME for Mid and Low Rectal Cancer

Launched by MANSOURA UNIVERSITY · Aug 3, 2017

Trial Information

Current as of May 15, 2025

Unknown status

Keywords

Minimally Invasive Surgery Trans Anal Total Mesorectal Excision Laparoscopic Total Mesoretal Excision

ClinConnect Summary

Colorectal cancer (CRC) is considered the third most common type of cancer all over the world and the fourth common cause of cancer-specific mortality.Surgical management for rectal cancer is challenging due to the narrow pelvis and extreme proximity to contiguous organs hence, recurrence rates are commonly reported.

The advent of total mesorectal excision (TME) together with minimally invasive techniques such as laparoscopic colorectal surgery have not only improved surgical results but have also improved surgical technique, operative ability and surgical visibility. Lap TME has been show...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. Anesthetically fit patient.
  • 2. Non metastatic pathologically proven rectal cancer (Mid-Low).
  • 3. Patients who received neoadjuvant chemo-radiotherapy will be included
  • Exclusion Criteria:
  • 1. Patients with American Society of Anesthesiologist (ASA) score 4 and 5.
  • 2. Patients with cardiac or chest problems that cannot withstand CO2 insufflation.
  • 3. Unresectable tumors (T4) (defined as those who cannot be resected without a high likelihood of leaving microscopic or gross residual disease at the local site because of tumor adherence or fixation).
  • 4. Obstructed or perforated cancer.
  • 5. Patients with unresectable metastatic rectal cancer.

About Mansoura University

Mansoura University is a prestigious academic institution located in Egypt, renowned for its commitment to advancing medical research and education. As a clinical trial sponsor, it leverages its extensive resources and expertise in various fields of healthcare to facilitate innovative research initiatives aimed at improving patient outcomes. The university collaborates with a network of healthcare professionals and researchers to conduct high-quality clinical trials, focusing on addressing critical health challenges through rigorous scientific methodologies. Its dedication to ethical research practices and adherence to regulatory standards underscores its role as a leader in the medical research community.

Locations

Mansoura, , Egypt

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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