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Search / Trial NCT03243539

Implementation of Neuro Lung Protective Ventilation

Launched by COLIN GRISSOM · Aug 7, 2017

Trial Information

Current as of May 20, 2025

Active, not recruiting

Keywords

Lung Protective Ventilation

ClinConnect Summary

This clinical trial is studying a new way to use ventilators for patients with acute brain injuries, such as strokes or traumatic brain injuries. When patients have lung injuries, they often need help breathing with a machine called a ventilator. However, if the settings on the ventilator are too high, it can actually harm the lungs further. This study aims to implement a computerized protocol that uses lower settings on the ventilator while still ensuring that the patient’s carbon dioxide levels remain normal, which is important for recovery.

To be eligible for this study, patients must be at least 18 years old and have an acute brain injury due to causes like strokes or bleeding in the brain. They must also begin using a ventilator in the emergency department or intensive care unit of an Intermountain Healthcare hospital. Participants can expect that their care will follow a new, standardized approach to mechanical ventilation, which may help improve their overall recovery. This study is currently active but not recruiting new participants.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. Acute brain injury due to non-traumatic causes (stroke, spontaneous intracranial hemorrhage, cerebral edema, anoxic brain injury) or traumatic brain injury.
  • 2. Initiation of mechanical ventilation in the emergency department or intensive care unit at an Intermountain Healthcare hospital
  • 3. Age ≥ 18 years
  • Exclusion Criteria:
  • 1. Transition to comfort care in the emergency department or on the same day of admission to the ICU
  • 2. Death on the same day of admission to the emergency department or ICU

About Colin Grissom

Colin Grissom is a dedicated clinical trial sponsor with a robust commitment to advancing medical research and improving patient outcomes. With extensive experience in the healthcare sector, he collaborates with leading institutions and researchers to facilitate innovative clinical studies across various therapeutic areas. His focus on rigorous methodology, ethical standards, and patient-centered approaches ensures the integrity and efficacy of each trial. Colin's leadership fosters a dynamic environment for scientific exploration, ultimately contributing to the development of novel treatments and enhancing the landscape of healthcare.

Locations

Murray, Utah, United States

Patients applied

0 patients applied

Trial Officials

Colin K Grissom, MD

Principal Investigator

Intermountain Health Care, Inc.

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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