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Search / Trial NCT03341403

Effect of a Synbiotic "Probiotical®/Bactecal® " in Asthma

Launched by UNIVERSITY OF LIEGE · Nov 10, 2017

Trial Information

Current as of May 11, 2025

Completed

Keywords

Severe Asthma Synbiotic Immunomodulation Sputum

ClinConnect Summary

Thirty percent of asthmatic patients are not well controlled even with an optimal treatment. There is then a need for new therapeutics allowing a better asthma control. Synbiotic (association of probiotics and prebiotics) have been shown to have anti-inflammatory properties as well as immunomodulatory activities. Moreover, synbiotic appeared to be very well tolerated and safe.

One hundred severe asthmatic patients (ACQ\> 1.5 and beclomethasone \> 200 µg per day) will receive "Probiotical ®/Bactecal®" (3 pills a day, content: Lactobacillus, Bifidobacterium et Streptococcus thermophilus, 18 ...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • severe asthma (ACQ \>1.5 and treatment = minimum 200 µg beclomethasone) and stable treatment for at least 3 months.
  • Exclusion Criteria:
  • treatment not stable
  • exacerbation state
  • infection

About University Of Liege

The University of Liège, a prestigious research institution in Belgium, is committed to advancing medical science through innovative clinical trials. With a focus on interdisciplinary collaboration, the university leverages its extensive expertise in various fields, including medicine, pharmacology, and biomedical engineering, to conduct high-quality research aimed at improving patient outcomes. The institution fosters a rigorous ethical framework and adheres to international standards in clinical research, ensuring the integrity and reliability of its studies. Through its clinical trials, the University of Liège aims to contribute significantly to the development of novel therapeutic approaches and enhance the understanding of complex health issues.

Locations

Liege, , Belgium

Patients applied

0 patients applied

Trial Officials

Renaud Louis, Prof.

Principal Investigator

CHU-ULG

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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