Explanations for Negative Laparoscopic Appendectomies and Normal Laparoscopies
Launched by HERLEV HOSPITAL · Nov 16, 2017
Trial Information
Current as of May 17, 2025
Completed
Keywords
ClinConnect Summary
Aim The aim of the study is to investigate which infectious diseases might mimic the symptoms of acute appendicitis to a degree that cause a diagnostic laparoscopy or laparoscopic appendectomy.
Primary outcome A comparison of the incidence of Yersinia spp. (enterocolitica and/or pseudotuberculosis) infection diagnosed by PCR on rectal swabs in the two groups: patients with histopathological confirmed inflammation (appendicitis group) and patients with one of the following: a histopathological normal appendix without inflammation, mesenteric lymphadenitis, or a normal diagnostic laparoscopy...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Suspicion of acute appendicitis and planned for diagnostic laparoscopy
- • Written informed consent after written and verbal information
- Exclusion Criteria:
- • Cannot understand, read or speak Danish
- • Known with inflammatory bowel disease
- • Other intra-abdominal pathology than appendicitis requiring other surgical intervention or treatment (diagnosed either perioperatively, at a preoperative CT-scan, or shortly after the surgery in the histopathological examination)
- • Not undergoing diagnostic laparoscopy, laparoscopic appendectomy, or open appendectomy
- • Use of antimicrobial agents within two weeks prior to inclusion until actual admission for acute abdominal pain
About Herlev Hospital
Herlev Hospital, a leading healthcare institution located in Denmark, is dedicated to advancing medical research and improving patient outcomes through innovative clinical trials. As a key player in the Danish healthcare system, Herlev Hospital combines cutting-edge facilities with a multidisciplinary approach to research, fostering collaborations among healthcare professionals and researchers. The hospital focuses on a wide range of medical fields, aiming to enhance treatment efficacy and patient care through rigorous scientific inquiry and ethical standards. With a commitment to excellence, Herlev Hospital plays a pivotal role in translating clinical research findings into practical applications that benefit patients and the broader community.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Herlev, Capital Region Of Denmark, Denmark
Patients applied
Trial Officials
Siv Fonnes, MD
Principal Investigator
Centre for Perioperative Optimization, Department of Surgery, Herlev and Gentofte Hospitals, University of Copenhagen
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Similar Trials