ClinConnect ClinConnect Logo
Search / Trial NCT03374670

ZIMURA in Combination With Eylea in Patients With Idiopathic Polypoidal Choroidal Vasculopathy (IPCV)

Launched by OPHTHOTECH CORPORATION · Dec 11, 2017

Trial Information

Current as of April 29, 2025

Withdrawn

Keywords

Zimura Arc1905 Eylea Aflibercept Ipcv Avacincaptad Pegol Complement Factor C5 Inhibitor

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Diagnosis of IPCV
  • Patients must have had 3 sequential Eylea injections within the previous 4 months
  • Exclusion Criteria:
  • Intravitreal treatment in the study eye prior to screening, regardless of indication, except 3 prior injections of Eylea
  • History or evidence of severe cardiac disease
  • Any major surgical procedure within one month of trial entry
  • Subjects with a clinically significant laboratory value
  • Any treatment with an investigational agent in the past 60 days for any condition
  • Women who are pregnant or nursing
  • Known serious allergies to the fluorescein dye, ICG dye, iodine, povidone iodine, or to the components or formulation of either Zimura or Eylea

About Ophthotech Corporation

Ophthotech Corporation is a clinical-stage biopharmaceutical company dedicated to developing innovative therapies for retinal diseases. With a focus on addressing unmet medical needs in conditions such as age-related macular degeneration and other vision-threatening disorders, Ophthotech is committed to advancing its proprietary drug candidates through rigorous clinical trials. The company's expertise in ophthalmology and its robust pipeline reflect a strong commitment to improving patient outcomes and enhancing the quality of life for individuals affected by debilitating eye diseases. Through strategic partnerships and a dedication to scientific excellence, Ophthotech aims to lead the way in transforming the landscape of retinal treatment.

Locations

'Aiea, Hawaii, United States

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Similar Trials