PIEB-PCEA vs CEI-PCEA for Abdominal Oncological Surgery. A Randomized Prospective Clinical Trial
Launched by PHILIPPS UNIVERSITY MARBURG · Dec 14, 2017
Trial Information
Current as of June 20, 2025
Completed
Keywords
ClinConnect Summary
Usually, patient controlled epidural analgesia (PCEA) is performed with a constant background infusion and patient-controlled bolus applications. An alternative approach is to give boluses at a regular rate for basic medication, instead of the continuous background infusion, maintaining the same amount of medication delivered per hour, (Programmed Intermittent Epidural Bolus injection; PIEB). In both cases, the patient has the option to trigger additional boluses. PIEB has been applied successfully in pain relief for lumbar epidural anesthesia in obstetrics, with better quality of analgesia...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Abdominal tumors in gynecology and general surgery
- • Enlightenment and written consent to the investigation
- Exclusion Criteria:
- • refusal to participate
- • pregnancy and breast feeding period
- • general contraindications for thoracic epidural anesthesia (e.g. coagulation disorders, --anticoagulation according to the guidelines of DGAI)
- • Impossibility to place the epidural catheter correctly
- • Known allergy to the drugs used in the study
- • Lack of understanding how to use the patient-controlled system
- • postoperative follow-up respiratory assistance
About Philipps University Marburg
Philipps University Marburg, established in 1527, is one of Germany's oldest universities and a leading institution in research and education. Known for its commitment to advancing medical science, the university actively sponsors clinical trials aimed at enhancing healthcare outcomes. With a focus on innovative therapies and interdisciplinary collaboration, Philipps University Marburg leverages its expertise in various medical fields to contribute to cutting-edge research and the development of new treatment modalities. Its robust infrastructure and dedication to ethical research practices ensure the integrity and efficacy of its clinical studies, making it a pivotal player in the advancement of medical knowledge.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Marburg, , Germany
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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