Impact of the Pre-phonatory Inspiratory Volume on the Speech Quality of Neuromuscular Patients Dependent on Non-invasive Ventilation
Launched by CENTRE D'INVESTIGATION CLINIQUE ET TECHNOLOGIQUE 805 · Dec 21, 2017
Trial Information
Current as of June 18, 2025
Unknown status
Keywords
ClinConnect Summary
Speech and communication quality depend on respiration efficiency. The respiratory involvement observed in neuromuscular disorders can impair speech quality in patients, while the underlying disease may also contribute to alter phonation.
Nowadays, the first line treatment of neuromuscular chronic neuromuscular respiratory failure is noninvasive ventilation (NIV). With disease progression, it is used with increasingly duration during daytime. In that situation, mouthpiece ventilation is preferred as it allows efficient ventilation while being more comfortable for patients who can chose whe...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • adult patients (age \> or equal to 18)
- • chronic restrictive respiratory failure due to neuromuscular disease
- • spontaneous breathing autonomy of at least one hour during the days
- • stable clinical state
- • patient with middle school education level (able to read)
- • patients using life support ventilator ((Astral 150 (ResMed®), Elysée (ResMed®), Trilogy (Philips Respironics®), VentilogicLS (Weinman®), Vivo 40 (Breas®), PB560 ou Légendair (Covidien®), Monal T50 (Air liquide system®))
- Exclusion Criteria:
- • refusal to participate
- • unability to cooperate
- • illiterate patients
- • tracheostomised patients
- • spontaneous breathing autonomy \< 1h
- • cardiovascular instability
- • not registered with the social security system
About Centre D'investigation Clinique Et Technologique 805
Centre d'Investigation Clinique et Technologique 805 is a leading research institution dedicated to advancing medical science through innovative clinical trials and technological development. With a focus on enhancing patient care and treatment outcomes, the center collaborates with healthcare professionals, academic institutions, and industry partners to conduct rigorous and ethically sound clinical research. By leveraging state-of-the-art facilities and a multidisciplinary team of experts, Centre 805 is committed to accelerating the translation of research findings into clinical practice, ultimately contributing to the betterment of public health.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Garches, , France
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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