Physiological Predictors of Clinical Outcomes After Anti-reflux Surgery

Launched by GUY'S AND ST THOMAS' NHS FOUNDATION TRUST · Dec 29, 2017

Keywords

ClinConnect Summary

This is a single centre, retrospective, cross-sectional study on patients who had anti-reflux surgery and pre-operative oesophageal physiology testing over 10 years. The investigators anticipate the recruitment of up to 350 subjects over 18 months.

Eligible patients will be contacted over the phone and asked whether they would be interested in joining the study. Candidates will be presented with details no less than the exact nature of the study, the implications and constraints of the protocol. Subjects will be made aware that no intervention will be made in this study, therefore taking p...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Males and non-pregnant females over the age of 18 years.
• • Gastro-oesophageal symptoms in accordance with Montreal criteria49
• • Patients who had oesophageal physiology testing at Guy's and St Thomas' NHS Foundation Trust
• • Oesophageal manometry based on Chicago classification
• • 24-hour standard pH, impedance-pH and Bravo™
• • Minimum 6 months post ARS and follow-up at GSTT
• • Verbal consent over the phone
• Exclusion Criteria:
• • Patients less than 18 years of age.
• • Pregnancy at the time of interview
• • Patients unable to comprehend or answer the questionnaires
• • Oesophageal physiology tests performed in other centres