Rapid Cortisol Assay in Adrenal Vein Sampling

Launched by UNIVERSITY HOSPITAL PADOVA · Feb 27, 2018

Keywords

ClinConnect Summary

Primary aldosteronism (PA) is a common form of hypertension caused by excess aldosterone secretion: it involves over 11% of the patients referred to specialized hypertension centres \[1\], about one fifth of those with drug-resistant hypertension \[2\] and about 6% of the hypertensive patients seen in general practice \[3\].

PA is held to cause cardiovascular disease in excess of the degree of blood pressure elevation, which translates into a high rate of cardiovascular events. These ominous consequences can be prevented with a timely diagnosis. Once the diagnosis of PA has been made, the ...

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Eligibility criteria

• • Inclusion Criteria: According to current guidelines consecutive patients with biochemical diagnosis of PA, who seek surgical cure of PA will be recruited for this study.These patients have a compelling indication to AVS before being referred or not for adrenalectomy.
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• • Exclusion Criteria: i) refusal of the center's to participate in the study; ii)refusal of the patientto undergo AVS and/or contraindications to the general anesthesia that is required for laparoscopic adrenalectomy; iii) cortisol -and aldosterone co-secreting adenoma.
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