Characterization of Cutaneous Microbiota in the Psoriasis Pathogenesis
Launched by I.R.C.C.S OSPEDALE GALEAZZI-SANT'AMBROGIO · Mar 22, 2018
Trial Information
Current as of May 23, 2025
Completed
Keywords
ClinConnect Summary
Twelve individuals with guttate psoriasis and 12 individuals with vulgaris psoriasis have been enrolled at Dermatological Unit of IRCCS Galeazzi Institute, Milan.
Patients selected for the psoriasis vulgaris group had a course of disease stable for at least 1 month before collection. The second group presented guttate psoriasis, defined as "eruptive", that is characterized by a rapid appearance and worsening of the clinical presentation within the month preceding the visit.
From each participant, a punch was used to obtain a cutaneous sample from both a lesion and healthy skin area of 2 m...
Gender
Eligibility criteria
- Inclusion Criteria:
- • over 18 years of age;
- • use of a free-preservatives soap with moisturizing function, applied once a day;pets.
- Exclusion Criteria:
- • no use of probiotics in the month prior the sampling;
- • no use of antibiotics in the month prior the sampling;
- • no treatment with corticosteroids, biological drugs, methotrexate or retinoids in the month prior the sampling;
- • no use of topical corticosteroids, vitamin D derivatives or phototherapy in the month prior the sampling;
- • no chronic or systemic infections;
- • no cutaneous acute infections during sampling;
- • no allergy to pollen, food and drugs
- • no pets.
About I.R.C.C.S Ospedale Galeazzi Sant'ambrogio
The I.R.C.C.S. Ospedale Galeazzi-Sant'Ambrogio is a leading clinical research institute and hospital in Italy, renowned for its commitment to advancing medical science through innovative research and high-quality patient care. As a designated Institute of Hospitalization and Care of Scientific Relevance (I.R.C.C.S.), it focuses on translational research that bridges the gap between laboratory findings and clinical applications. The facility is equipped with state-of-the-art technology and a multidisciplinary team of experts, enabling it to conduct a wide range of clinical trials aimed at improving treatment outcomes across various medical fields. Its dedication to ethical practices and patient safety ensures that all research activities align with the highest international standards.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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