The Predictive Value of Alarm Symptoms in Patients With Dyspepsia Based on Roman IV

Launched by SECOND AFFILIATED HOSPITAL OF XI'AN JIAOTONG UNIVERSITY · Mar 24, 2018

Keywords

ClinConnect Summary

Functional dyspepsia is one of the most common gastrointestinal disorders (FGIDs) encountered in clinical practice. Functional dyspepsia is a clinical syndrome characterized by chronic and recurrent gastroduodenal symptoms in the absence of any organic or metabolic disease that is likely to explain the symptoms.Functional dyspepsia has a high incidence in the population.Clinical diagnosis is notoriously unreliable in diagnosing the underlying cause of dyspepsia,but a number of alarm features have been suggested as indicating patients at higher risk for serious disease.However, previous stud...

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Eligibility criteria

• Inclusion criteria:
• • 1. Aged 18 years and older;
• • 2. Presence of dyspeptic symptoms according with Rome IV criteria (Discomfort was characterized by the presence of one or more symptoms that included bothersome postprandial fullness, bothersome early satiation, bothersome epigastric pain, bothersome epigastric burning, Symptoms had to be present for at least 3 months within the preceding 6 months);
• • 3. From March 2018 to January 2019, patient went to the Gastroenterology clinics of the second affiliated hospital of xi'an jiaotong university, Xijing Hospital, Tangdu Hospital, Xi'an No.3 Hospital, and received gastroscopy;
• • 4. Upper abdominal ultrasonography, blood routine examination, liver function test were conducted within six months.
• Exclusion criteria:
• • 1. History of esophagitis or ulcer disease or other organic upper gastrointestinal disease, pancreaticobiliary disease, metabolic disease(abnormal thyroid function, diabetes );
• • 2. Were pregnant, might become pregnant, or were lactating;
• • 3. Major abdominal surgery;
• • 4. Severe neurological disorder, psychological diseases; or with severe hepatic, renal or respiratory dysfunction;
• • 5. Known or suspected liver dysfunction, including NASH, HBV or HCV-related hepatitis;
• • 6. History of gastroscope within 1 year;
• • (6) Current antidepressant, steroids or NSAID use; (7) Patients who had only reflux-related symptoms or who had predominantly reflux-related symptoms; (8) Not willing to participate in the study.