Lactoferrin Versus Ferrous Sulphate for Treatment of Iron Deficiency Anaemia During Pregnancy

Launched by AIN SHAMS MATERNITY HOSPITAL · Mar 22, 2018

Keywords

ClinConnect Summary

Lactoferrin and Ferrous sulfate are used to treat iron deficiency anemia in pregnancy.

Ferrous sulphate is the most commonly used treatment for iron deficiency anemia.

Lactoferrin is a new generation oral iron that has long been recognized as a member of the transferrin family of proteins and an important regulator of the levels of free iron in the body fluids and has the ability to enhance iron binding. Preliminary evidence suggests that lactoferrin may represent a promising new strategy for oral iron replacement.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Pregnant women with single fetus
• • Hb count \< 11g/dL
• • ferritin level \< 12 ng/dL
• • Gestational age (14 - 30 weeks)
• Exclusion Criteria:
• • Associated chronic medical disorder (CKD, liver disease, peptic ulcer and chronic blood loss).
• • Associated bleeding disorder
• • Anaemia requiring blood tranfusion (Hb \< 7g/dL)
• • Hypersensitivity to iron preparations
• • Haemoglobinopathies (G6PD, thalassemias, sickle cell disease)